--- title: "Real-world data for heart failure: Closing evidence gaps across the patient journey" description: Discover how taXonomy Pathways connects claims, labs, and EHR to reveal real-world insights in congestive heart failure research and heart failure outcomes. image: https://blog.healthverity.com/hubfs/real-world-data-for-heart-failure-featured.png --- Announcing HealthVerity Precision Event Alerts, a next-generation physician alerting solution. [Learn more](https://healthverity.com/news/healthverity-precision-event-alerts-launch/) - [Contact](https://healthverity.com/contact/) - [Sign In](https://marketplace.healthverity.com/login/?next=/marketplace/) [![HealthVerity-Logo-Dark-3](https://blog.healthverity.com/hs-fs/hubfs/HealthVerity-Logo-Dark-3.png?width=1662&height=320&name=HealthVerity-Logo-Dark-3.png)](https://healthverity.com/) - How We Help - Featured Content - [HealthVerity MarketplaceTM](https://healthverity.com/marketplace/healthverity-marketplace/) - [HealthVerity TaxonomySM](https://healthverity.com/taxonomy-portal/) - [Life Sciences](https://healthverity.com/life-sciences/) - [Identity Manager (HVID)](https://healthverity.com/identity-manager/) - Data Ecosystem - [HealthVerity MarketplaceTM](https://healthverity.com/marketplace/healthverity-marketplace/) - [HealthVerity TaxonomySM](https://healthverity.com/taxonomy-portal/) - [Precision Event Alerts](https://healthverity.com/precision-event-alerts/) - [HealthVerity Mastersets](https://healthverity.com/mastersets/portal/) - [Media Measurement](https://healthverity.com/media-measurement/) - [Insurance Underwriting](https://healthverity.com/insurance-underwriting/) - Technology Products - [Identity Manager (HVID)](https://healthverity.com/identity-manager/) - [HealthVerity FLOW](https://healthverity.com/flow/portal/) - [Governance Manager](https://healthverity.com/governance-manager/) - [Smart Contracts](https://healthverity.com/smart-contracts-manager/) - Symphony - Symphony Health Platform - [Symphony Health Overview](https://healthverity.com/symphony-health/overview/) - [Integrated Dataverse](https://healthverity.com/symphony-health/integrated-dataverse-and-source-solutions/) - [Symphony HealthCloud](https://healthverity.com/symphony-health/health-technology-and-business-intelligence-solutions/) - Symphony Solutions - [Health technology and business intelligence solutions](https://healthverity.com/symphony-health/health-technology-and-business-intelligence-solutions/) - [Integrated Dataverse and Source Solutions](https://healthverity.com/symphony-health/integrated-dataverse-and-source-solutions/) - [Brand strategy and sales](https://healthverity.com/symphony-health/optimize-brand-strategy-and-sales-effectiveness/) - [HealthRankings](https://healthverity.com/symphony-health/health-rankings/) - [Market access](https://healthverity.com/symphony-health/solve-market-access-challenges/) - [Patient Journey](https://healthverity.com/symphony-health/understand-the-patient-journey/) - [Medicines affordability](https://healthverity.com/symphony-health/making-medicines-more-affordable/) - Symphony Products - [PayerSource®](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-PayerSource.pdf) - [PrescriberSource®](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-PrescriberSource.pdf) - [PatientSource®](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-PatientSource.pdf) - [PatientSourceCompleteTM](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-PatientSourceComplete.pdf) - [PatientSourceDUOTM](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-PatientSourceDUO.pdf) - [Symphony FLEXTM](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-Symphony-FLEX.pdf) - [CustomerSource®](https://healthverity.com/symphony-health/integrated-dataverse-and-source-solutions/) - [DiagnosticSource®](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-DiagnosticSource.pdf) - [NonRetailSource®](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-NonRetailSource.pdf) - Symphony Technology - [Symphony HealthCloud](https://healthverity.com/symphony-health/health-technology-and-business-intelligence-solutions/) - [Synoma Data Integration](https://healthverity.com/symphony-health/health-technology-and-business-intelligence-solutions/) - [Vantage Applications](https://blog.healthverity.com/hubfs/HealthVerity-Symphony-PDFs/HealthVerity-Symphony-Health-Factsheet-Vantage-Applications.pdf) - [Metys](https://healthverity.com/symphony-health/health-technology-and-business-intelligence-solutions/metys/) - Who We Serve - [Life Sciences](https://healthverity.com/life-sciences/) - [Government](https://healthverity.com/government/) - [Insurance](https://healthverity.com/insurance/) - [Channel Partners](https://healthverity.com/channel-partners/) - [Data Ecosystem Partners](https://healthverity.com/data-ecosystem-partners/) - Resources - [HealthVerity Blog](https://blog.healthverity.com/) - [News & Events](https://healthverity.com/resources/news-and-events/) - [Resource Library](https://healthverity.com/resources/resource-library/) - [Publications](https://healthverity.com/resources/publications/) - [The IPGE Approach](https://healthverity.com/ipge-approach/) - [Zombie Data Explained](https://healthverity.com/get-verified/) - [Careers](https://healthverity.com/careers/) - [About Us](https://healthverity.com/about-us/) [Request Demo](https://healthverity.com/request-demo/) [Contact](https://healthverity.com/contact/) [Sign In](https://marketplace.healthverity.com/) [![Logo](https://blog.healthverity.com/hubfs/social-suggested-images/healthverity.comwp-contentuploadshealthverity-2023-logo2x.png)](https://healthverity.com/) - How We Help - Symphony - Who We Serve - Resources - [Careers](https://healthverity.com/careers/) - [About Us](https://healthverity.com/about-us/) [Request Demo](https://healthverity.com/request-demo/) Featured Content ###### HealthVerity MarketplaceTM The nation’s largest healthcare and consumer data ecosystem ###### taXonomy Pathways Unique features per therapeutic area with claims, labs and EHR including notes ###### HealthVerity eXOs AI-native real-world evidence generation ###### Identity Manager (HVID) Standalone de-identification as a service Data Ecosystem HealthVerity MarketplaceTM HealthVerity TaxonomySM HealthVerity Notes Precision Event Alerts HealthVerity Mastersets Media Measurement Syndicated Audiences Insurance Underwriting Technology Products Identity Manager (HVID) HealthVerity for Clinical Trial Linkage HealthVerity for Commercial Smart Contracts HealthVerity for Registries Symphony Health Platform ###### Symphony Health Overview Seamless Data. Stronger Insights. Smarter Decisions. ###### Integrated Dataverse Integrated Dataverse (IDV®) is de-identified claims data platform that combines medical, hospital, prescription, and demographic data into a single unifed view. ###### Symphony HealthCloud Securely store, integrate, access, and analyze virtually unlimited volumes of data with Symphony HealthCloud. Symphony Solutions Health technology and business intelligence solutions Integrated Dataverse and Source Solutions Brand strategy and sales HealthRankings Market access Patient Journey Medicines affordability Symphony Products PayerSource® PrescriberSource® PatientSource® PatientSourceCompleteTM PatientSourceDUOTM Symphony FLEXTM CustomerSource® DiagnosticSource® NonRetailSource® Symphony Technology Symphony HealthCloud Synoma Data Integration Vantage Applications Metys ###### Life Sciences Technology solutions from development through commercialization ###### Channel Partners HealthVerity enables partners to unlock unprecedented value and insights for clients ###### Government Comprehensive and compliant solutions to manage the nation’s care ###### Data Ecosystem Partners Join the nation’s largest data partner ecosystem ###### Insurance Insurance-grade solutions that excel in managing risk and rebates ###### HealthVerity Blog Insights and updates from industry experts ###### Publications Peer-reviewed research and discoveries ###### News & Events Stay informed about our latest announcements and happenings ###### The IPGE Approach Fundamentals that power everything that we do and every solution we offer ###### Resource Library Explore guides, webinars, and tools to enhance your understanding ###### Zombie Data Explained Learn how data quality drives better research outcomes [Solutions & Best Practices](https://blog.healthverity.com/tag/solutions-best-practices), [Open & Closed Claims](https://blog.healthverity.com/tag/open-closed-claims) # Real-world data for heart failure: Closing evidence gaps across the patient journey [By \- HealthVerity,](https://blog.healthverity.com/author/healthverity) October 16, 2025 ![](https://blog.healthverity.com/hubfs/real-world-data-for-heart-failure-featured.png) ## The evolution of heart failure treatment and research Heart failure remains one of the most prevalent and costly chronic diseases in the United States, affecting more than 6.7 million adults and projected to reach 8.7 million by 2030.1 It is the leading cause of hospitalization in adults over 65 y/o and contributes to over 400,000 deaths annually, accounting for roughly 45% of cardiovascular mortality.1 In 2020, total direct and indirect heart failure costs reached $46 billion, a figure expected to more than triple by 2050 as prevalence rises.1  Over the past decade, breakthroughs in pharmacologic and device therapy have transformed how heart failure such as congestive heart failure (CHF) is managed. The PARADIGM-HF trial established sacubitril/valsartan (Entresto®) as the first therapy to significantly reduce mortality and hospitalization versus enalapril, setting a new standard of care for patients with reduced ejection fraction (HFrEF).2 Soon after, a newer class of drugs known as SGLT2 inhibitors that were originally developed for diabetes showed strong benefits for patients with heart failure. In large clinical trials, dapagliflozin (Farxiga®) and empagliflozin (Jardiance®) were proven to reduce hospitalizations and improve survival for patients whose hearts have reduced ejection fraction (reduced pumping function), and later for those with preserved ejection fraction (normal pumping function).3,4 These results were exciting and welcome because they expanded heart failure treatment to millions of patients who previously had few effective options. [![taxonomy-pathways-diagram-alt](https://blog.healthverity.com/hs-fs/hubfs/taxonomy-pathways-diagram-alt.png?width=705&height=312&name=taxonomy-pathways-diagram-alt.png)](https://healthverity.com/pathways/)Figure 1: Closing the evidence gap in CHF research with [taXonomy Pathways.](https://healthverity.com/pathways/)   These advances were then followed by vericiguat (Verquvo®), a soluble guanylate-cyclase stimulator shown in VICTORIA to reduce HF hospitalizations among high-risk patients,5 and by tafamidis (Vyndaqel®)6, which became the first FDA-approved therapy for transthyretin amyloid cardiomyopathy (ATTR-CM), addressing a major underdiagnosed cause of HF in older adults.7 Meanwhile, ongoing trials are exploring next-generation mechanisms such as myosin activators and relaxin agonists to gene and cell-based therapies aimed at reversing myocardial dysfunction rather than simply managing it.8  Recent device innovations are improving CHF care by enabling closer monitoring and smarter intervention through the use of implantable sensors like CardioMEMS and Cordella. Clinicians can monitor pulmonary artery pressure in real time from patient homes, lowering hospitalization risk.9 Institutions are also testing newer tools like left atrial pressure sensors, noninvasive lung-fluid monitors, wearable patches, and neuromodulation or contractility-enhancing devices for patients whose disease remains refractory.  Beyond therapies and hardware, heart failure care is rapidly evolving through remote monitoring, virtual care, and AI prediction tools. For instance, the American Heart Association recently launched a remote support program combining 24/7 virtual monitoring, clinical oversight, and guideline-based care to reduce 30-day readmissions in HF patients by catching decompensation early at home.10 While still in pilot phases, these hybrid models are reshaping the post-hospital care and creating new continuous data streams of symptom reports and alerts. With this innovation, comes complexity. Researchers and pharmaceutical manufacturers are asking: How well do these therapies perform in routine practice? Which subgroups benefit most? And what are the long-term effects across diverse populations? Answering these questions requires more than just closed claims data (Figure 1). [![Close the evidence gap with taXonomy Pathways](https://no-cache.hubspot.com/cta/default/5412465/interactive-196135223637.png)](https://blog.healthverity.com/hs/cta/wi/redirect?encryptedPayload=AVxigLJaqNutHIMFi6mrnfpF56v8wiIKqvTzgOvEg%2FNBR%2BudyonfPuldKBltb1svzXLsUOroEYMf2aGPullZSOGf%2BoUa31DSIfaqvEn5ybVkka8%2BuiNn4f2VF%2BOaqeh4%2FrclIc%2Fkm018%2F3gDtfWWC1ee2VIdw4cGHBvnEhtmjt14m09fSJkV8p4Kp6asOxU1OobB6UjcOK8707D8&webInteractiveContentId=196135223637&portalId=5412465)   ## Why claims data alone can’t explain real-world heart failure outcomes Claims data remain essential for tracking hospitalizations, procedures, and medication use, but they miss the clinical nuance that defines heart failure management. For example: - **Ejection fraction (EF):** Claims cannot distinguish between reduced and preserved EF, even though treatment differs. - **Cardiac biomarkers:** NT-proBNP, creatinine, and hemoglobin A1c values are rarely captured in claims yet determine disease stage, prognosis, and eligibility for specific therapies. - **Adverse events and discontinuation reasons:** Claims record that a prescription stopped but not the reason… whether due to hypotension, renal decline, or patient intolerance. - **Physician documented symptoms:** Notes describe shortness of breath, edema, or fatigue severity, which guide titration but are invisible in claims. Without these data, researchers can’t accurately measure treatment response, adherence, or safety. For example, a claim may show that a patient filled sacubitril/valsartan once, but lab data might reveal rising creatinine that led to discontinuation, or notes might document symptomatic improvement that claims don't capture (Figure 2) ![chf tp](https://blog.healthverity.com/hs-fs/hubfs/chf%20tp.png?width=635&height=279&name=chf%20tp.png) Figure 2: Example of a CHF pathway ## The research opportunity connecting claims with real-world data The opportunity for manufacturers, researchers, and healthcare stakeholders is to bridge this data gap and gain a comprehensive view of the heart failure treatment journey. By integrating closed payer claims with laboratory results and EHR, including physician notes, researchers can uncover insights that were previously hidden. This is particularly valuable for teams in health economics and outcomes research (HEOR), epidemiology, and pharmacovigilance who are tasked with evaluating real-world performance and long-term outcomes of heart failure therapies. With the right data: - **Health economics and outcomes research (HEOR)** analysts can link hospital utilization and pharmacy costs to changes in biomarkers such as NT-proBNP or renal function, quantifying the real-world value of quadruple therapy. - **Epidemiologists** can identify which subgroups of HFpEF patients respond best to SGLT2 inhibitors by stratifying cohorts by EF range, age, or comorbidities. - **Safety and pharmacovigilance** teams can detect emerging signals like hypotension or kidney function changes by correlating claims with serial lab values and clinician notes. - **Market access** teams can demonstrate treatment persistence and hospitalization reductions by payer, region, or provider network, strengthening the evidence base for coverage decisions. These insights simply aren’t possible with claims alone. They require longitudinal datasets that combine utilization, clinical measures, and narrative context to show how therapies perform in everyday care (Figure 2). ## The taXonomy Pathways solution [taXonomy Pathways](https://healthverity.com/pathways/) brings together closed payer claims, laboratory data, and EHR, including physician notes, to reveal the complete heart failure journey with a focus on CHF the most clinically complex and costly form of the disease. The CHF dataset is anchored by the nation’s largest closed claims universe, spanning hundreds of payers and covering more than **6.4 million de-identified CHF patients** across nine years of adjudicated medical and pharmacy history. Over **5.8 million also have pharmacy claims**. This foundation is enriched with laboratory data from the two largest U.S. outpatient networks, representing over **60% of all cardiac biomarker testing**, and EHR data including millions of clinical notes that capture disease severity, hospital course, and recovery patterns. What makes taXonomy Pathways unique is the **depth of biomarker coverage** across its heart failure datasets. It captures cardiac and renal measures such as NT-proBNP, BNP, troponin, eGFR, and sodium for millions of patients. These data points that are often unavailable from competing real-world data sources. This clinical granularity enables direct assessment of disease severity, treatment response, and safety signals in ways that claims-only datasets simply cannot support. Within this combined dataset, researchers can analyze: - **Ejection fraction (EF) and imaging results** to classify reduced versus preserved EF in CHF cohorts. - **Key biomarkers** such as NT-proBNP, BNP, creatinine, sodium, and troponin to track congestion status, renal function, and therapy response. - **Medication utilization and titration patterns** across ARNI, beta-blockers, MRA, SGLT2 inhibitors, and loop diuretics to understand adherence and real-world optimization. - **Readmission and hospitalization trends**, including length of stay and 30-day readmission rates linked to baseline lab values. - **Reasons for discontinuation or non-response** drawn from physician notes, including hypotension, worsening renal function, or symptomatic improvement leading to dose adjustment. By connecting claims with detailed clinical data, [taXonomy Pathways](https://healthverity.com/pathways/) enables researchers and manufacturers to quantify outcomes that claims alone cannot show—such as how early biomarker improvement predicts reduced rehospitalization, or how renal trends inform treatment adjustments. This integrated, research-ready CHF dataset allows HEOR, RWE, and epidemiology teams to evaluate real-world treatment effectiveness, safety, and progression in one place, without the complexity of stitching together fragmented data sources. [Watch our webinar](https://info.healthverity.com/closing-the-evidence-gap-before-year-end) where we dive deeper into CHF real-world evidence. In the meantime, if you are exploring heart failure or other cardiovascular disease outcomes, we can help design a tailored real-world study. Tell us your population of interest and endpoints. With taXonomy Pathways, we will deliver a dataset and analysis framework that **you simply cannot see in claims data alone.** **Interested in getting started with taXonomy Pathways? [Download](https://blog.healthverity.com/hubfs/guide-to-comprehensive-patient-journeys.pdf) our guide to comprehensive patient outcomes.** [![Close the evidence gap with taXonomy Pathways](https://no-cache.hubspot.com/cta/default/5412465/interactive-196135223637.png)](https://blog.healthverity.com/hs/cta/wi/redirect?encryptedPayload=AVxigLJaqNutHIMFi6mrnfpF56v8wiIKqvTzgOvEg%2FNBR%2BudyonfPuldKBltb1svzXLsUOroEYMf2aGPullZSOGf%2BoUa31DSIfaqvEn5ybVkka8%2BuiNn4f2VF%2BOaqeh4%2FrclIc%2Fkm018%2F3gDtfWWC1ee2VIdw4cGHBvnEhtmjt14m09fSJkV8p4Kp6asOxU1OobB6UjcOK8707D8&webInteractiveContentId=196135223637&portalId=5412465) ## References 1. Fonarow GC, Ahmad FS, Ahmad T, et al. Hf stats 2025: heart failure epidemiology and outcomes statistics an updated 2025 report from the heart failure society of america. *Journal of Cardiac Failure*. Published online September 2025. [https://onlinejcf.com/article/S1071-9164(25)00326-4/fulltext](https://onlinejcf.com/article/S1071-9164(25)00326-4/fulltext) 2. McMurray JJV, Packer M, Desai AS, et al. Angiotensin–neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371(11):993-1004. [https://www.nejm.org/doi/full/10.1056/NEJMoa1409077](https://www.nejm.org/doi/full/10.1056/NEJMoa1409077) 3. McMurray JJV, Solomon SD, Inzucchi SE, et al. Dapagliflozin in patients with heart failure and reduced ejection fraction. N Engl J Med. 2019;381(21):1995-2008. [https://www.nejm.org/doi/full/10.1056/NEJMoa1911303](https://www.nejm.org/doi/full/10.1056/NEJMoa1911303) 4. Anker SD, Butler J, Filippatos G, et al. Empagliflozin in heart failure with a preserved ejection fraction. N Engl J Med. 2021;385(16):1451-1461. doi:10.1056/NEJMoa21070 5. Armstrong PW, Pieske B, Anstrom KJ, et al. Vericiguat in patients with heart failure and reduced ejection fraction. N Engl J Med. 2020;382(20):1883-1893. doi:10.1056/NEJMoa1915928 6. Maurer MS, Schwartz JH, Gundapaneni B, et al. Tafamidis treatment for patients with transthyretin amyloid cardiomyopathy. N Engl J Med. 2018;379(11):1007-1016. doi:10.1056/NEJMoa1805689 7. TrueParallel. Askbio presents complete results of phase 1 trial of ab-1002 gene therapy in participants with congestive heart failure at european society of cardiology heart failure meeting. AskBio. May 19, 2025. Accessed October 13, 2025. (NCT04179643) [https://www.askbio.com/askbio-presents-complete-results-of-phase-1-trial-of-ab-1002-gene-therapy-in-participants-with-congestive-heart-failure-at-european-society-of-cardiology-heart-failure-meeting](https://www.askbio.com/askbio-presents-complete-results-of-phase-1-trial-of-ab-1002-gene-therapy-in-participants-with-congestive-heart-failure-at-european-society-of-cardiology-heart-failure-meeting/) 8. Teerlink JR, Diaz R, Felker GM, et al. Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction: rationale and design of galactic-hf. JACC Heart Fail. 2020;8(4):329-340. doi:10.1016/j.jchf.2019.12.001 9. Batcheldor M. 100th patient receives ambulatory heart failure device. VUMC News. May 11, 2023. Accessed October 14, 2025. [https://news.vumc.org/2023/05/11/new-device-offers-peace-of-mind-to-heart-failure-patients/](https://news.vumc.org/2023/05/11/new-device-offers-peace-of-mind-to-heart-failure-patients/) 10. Novel virtual care program enhances at-home support for people with heart failure. American Heart Association. Accessed October 14, 2025. [https://newsroom.heart.org/news/novel-virtual-care-program-enhances-at-home-support-for-people-with-heart-failure](https://newsroom.heart.org/news/novel-virtual-care-program-enhances-at-home-support-for-people-with-heart-failure)   [![Explore RWD in HealthVerity Marketplace™](https://no-cache.hubspot.com/cta/default/5412465/interactive-195733501532.png)](https://blog.healthverity.com/hs/cta/wi/redirect?encryptedPayload=AVxigLLzrofr3eKHskcEulGcnbgi7wYJxtaL9RhSCkqTGJNBSjdjrX0uYEjFOIGFot6gYG1h5cw1xAx3JaBWTkM5raYNEwgZHqmEdr6m7un%2F2%2FrE5Xmyrn9kZ2K5PIbaElLHdv0lLMvzVUet86qCoPN2SBwI8Pq5GzlUpSbB46OTC8BB9MuCX30yctDJCDhwn16d%2FW4NE2pErGDGYV%2Fk&webInteractiveContentId=195733501532&portalId=5412465) ###### Category - [Solutions & Best Practices](https://blog.healthverity.com/tag/solutions-best-practices) - [Trends & Insights](https://blog.healthverity.com/tag/trends-insights) - [HEOR](https://blog.healthverity.com/tag/heor) - [Marketplace (RWD)](https://blog.healthverity.com/tag/marketplace-rwd) - [Thought Leadership](https://blog.healthverity.com/tag/thought-leadership) - [Industry Updates](https://blog.healthverity.com/tag/industry-updates) - [Open & Closed Claims](https://blog.healthverity.com/tag/open-closed-claims) - [Case Studies](https://blog.healthverity.com/tag/case-studies) - [Commercial Pharma](https://blog.healthverity.com/tag/commercial-pharma) - [Government](https://blog.healthverity.com/tag/government) - [AI](https://blog.healthverity.com/tag/ai) - [eXOs](https://blog.healthverity.com/tag/exos) - [Audiences](https://blog.healthverity.com/tag/audiences) - [taXonomy Pathways](https://blog.healthverity.com/tag/taxonomy-pathways) - [Clinical Notes](https://blog.healthverity.com/tag/clinical-notes) - [Rare Diseases](https://blog.healthverity.com/tag/rare-diseases) ###### Popular Post - [The GLP-1 trend: What the real-world data reveals](https://blog.healthverity.com/the-glp-1-surge-what-the-real-world-data-reveals) - [GLP-1 trends 2025: real-world data, patient outcomes & future therapies](https://blog.healthverity.com/glp-1-trends-2025-real-world-data-patient-outcomes-future-therapies) - [Open claims vs. closed payer claims: What’s the difference?](https://blog.healthverity.com/open-claims-vs-closed-payer-claims) - [An integrated approach for deeper insight with both open and closed claims data](https://blog.healthverity.com/an-integrated-approach-for-deeper-insight-with-both-open-and-closed-claims-data) - [GLP‑1 real‑world data for obesity: A new standard for metabolic care](https://blog.healthverity.com/glp-1-real-world-data-for-obesity-a-new-standard-for-metabolic-care) ###### Subscribe ### Similar Blogs [![More than data: Synchronizing the breast cancer patient story](https://blog.healthverity.com/hs-fs/hubfs/more-than-data-synchronizing-the-breast-cancer-patient-story.jpg?width=352&name=more-than-data-synchronizing-the-breast-cancer-patient-story.jpg)](https://blog.healthverity.com/breast-cancer-patient-story) #### [More than data: Synchronizing the breast cancer patient story](https://blog.healthverity.com/breast-cancer-patient-story) By [HealthVerity](https://blog.healthverity.com/author/healthverity) 25 October 2023 One in eight women in the U.S. will be diagnosed with breast cancer in their lifetime, that’s one... [READ MORE](https://blog.healthverity.com/real-world-data-for-heart-failure-closing-evidence-gaps-across-the-patient-journey) [![How taXonomy Pathways builds comprehensive patient journeys](https://blog.healthverity.com/hs-fs/hubfs/pathways-blog-featured.png?width=352&name=pathways-blog-featured.png)](https://blog.healthverity.com/how-taxonomy-pathways-builds-comprehensive-patient-journeys) #### [How taXonomy Pathways builds comprehensive patient journeys](https://blog.healthverity.com/how-taxonomy-pathways-builds-comprehensive-patient-journeys) By [HealthVerity](https://blog.healthverity.com/author/healthverity) 21 October 2025 In a recent webinar, the HealthVerity team including Alexa Woodward, Ph.D., Director of Strategic... [READ MORE](https://blog.healthverity.com/real-world-data-for-heart-failure-closing-evidence-gaps-across-the-patient-journey) [![How GLP-1 direct-to-consumer programs are distorting utilization trends](https://blog.healthverity.com/hs-fs/hubfs/glp-1-dtc-blog.png?width=352&name=glp-1-dtc-blog.png)](https://blog.healthverity.com/how-glp-1-direct-to-consumer-programs-are-distorting-utilization-trends) #### [How GLP-1 direct-to-consumer programs are distorting utilization trends](https://blog.healthverity.com/how-glp-1-direct-to-consumer-programs-are-distorting-utilization-trends) By [HealthVerity](https://blog.healthverity.com/author/healthverity) 14 January 2026 Closed claims no longer reflect real-world GLP-1 treatment patterns GLP-1 utilization continues to... [READ MORE](https://blog.healthverity.com/real-world-data-for-heart-failure-closing-evidence-gaps-across-the-patient-journey) #### Who we serve - [Life Sciences](https://healthverity.com/life-sciences/) - [Government](https://healthverity.com/government/) - [Insurance](https://healthverity.com/insurance/) - [Channel Partners](https://healthverity.com/channel-partners/) - [Data Ecosystem Partners](https://healthverity.com/data-ecosystem-partners/) #### How we help - [HealthVerity Marketplace](https://healthverity.com/marketplace/) - [HealthVerity Mastersets](https://healthverity.com/mastersets/) - [HealthVerity FLOW](https://healthverity.com/flow/) - [The IPGE Approach](https://healthverity.com/ipge-approach/) #### Resources - [HealthVerity Blog](https://blog.healthverity.com/) - [News & Events](https://healthverity.com/resources/news-and-events/) - [Resource Library](https://healthverity.com/resources/resource-library/) - [Publications](https://healthverity.com/resources/publications/) #### Our company - [About Us](https://healthverity.com/about-us/) - [Leadership](https://healthverity.com/about-us/#leadership) - [Board of Directors](https://healthverity.com/about-us/#board) - [Careers](https://healthverity.com/careers/) - [Contact](https://healthverity.com/contact/) ©2026 HealthVerity, Inc.    |    [Terms & Conditions](https://healthverity.com/terms-and-conditions/)    |    [Privacy Policy](https://healthverity.com/privacy-policy/)